Rat poop, bug bits, mice hair: How many ‘unavoidable defects’ are in peanut butter and other foods you eat? | CNN



CNN
 — 

Brace yourselves, America: Many of your favorite foods may contain bits and pieces of creatures that you probably didn’t know were there.

How about some mice dung in your coffee? Maggots in your pizza sauce? Bug fragments and rat hair in your peanut butter and jelly sandwich?

Oh, and so sorry, chocolate lovers. That dark, delicious bar you devoured might contain 30 or more insect parts and a sprinkling of rodent hair.

Called “food defects,” these dismembered creatures and their excrement are the unfortunate byproduct of growing and harvesting food.

“It is economically impractical to grow, harvest, or process raw products that are totally free of non-hazardous, naturally occurring, unavoidable defects,” the US Food and Drug Administration said.

So while there’s no way to get rid of all the creatures that might hitch a ride along the food processing chain, the FDA has established standards to keep food defects to a minimum.

Let’s go through a typical day of meals to see what else you’re not aware that you’re eating.

The coffee beans you grind for breakfast are allowed by the FDA to have an average of 10 milligrams or more animal poop per pound. As much as 4% to 6% of beans by count are also allowed to be insect-infested or moldy.

As you sprinkle black pepper on your morning eggs, try not to think about the fact you may be eating more than 40 insect fragments with every teaspoon, along with a smidgen of rodent hair.

Did you have fruit for breakfast? Common fruit flies can catch a ride anywhere from field to harvest to grocery store, getting trapped by processors or freezing in refrigerated delivery trucks and ending up in your home.

Let’s say you packed peanut butter and jelly sandwiches for everyone’s lunch. Good choice!

Peanut butter is one of the most controlled foods in the FDA list; an average of one or more rodent hairs and 30 (or so) insect fragments are allowed for every 100 grams, which is 3.5 ounces.

The typical serving size for peanut butter is 2 tablespoons (unless you slather). That means each 2 tablespoon-peanut butter sandwich would only have about eight insect fragments and a teensy bit of rodent filth. (“Filth” is what the FDA calls these insect and rodent food defects.)

Unfortunately, jelly and jam are not as controlled. Apple butter can contain an average of four or more rodent hairs for every 3.5 ounces (100 grams) and about five whole insects. Oh, and that isn’t counting the unknown numbers of teensy mites, aphids and thrips.

Apple butter can also contain up to 12% mold, which is better than cherry jam, which can be 30% moldy, or black currant jam, which can be 75% moldy.

Did you pack some of the kid-size boxes of raisins for your child’s midafternoon snack?

Golden raisins are allowed to contain 35 fruit fly eggs as well as 10 or more whole insects (or their equivalent heads and legs) for every 8 ounces. Kid-size containers of raisins are an ounce each. That’s more than four eggs and a whole insect in each box.

Any Bloody Mary fans? The tomato juice in that 14-ounce Bloody Mary could contain up to four maggots and 20 or more fruit fly eggs.

And if you’re having a fruity cocktail, just be aware that the canned citrus juices that many bars use can legally have five or more fruit fly eggs or other fly eggs per cup (a little less than 250 milliliters). Or that cup of juice could contain one or more maggots. Apricot, peach and pear nectars are allowed to contain up to 12% moldy fruit.

Oh, gosh, the possibilities are endless! Did you know there can be 450 insect parts and nine rodent hairs in every 16-ounce box of spaghetti?

Canned tomatoes, tomato paste and sauces such as pizza sauce are a bit less contaminated than the tomato juice in your cocktail. The FDA only allows about two maggots in a 16-ounce can.

Adding mushrooms to your spaghetti sauce or pizza? For every 4-ounce can of mushrooms there can be an average of 20 or more maggots of any size.

The canned sweet corn we love is allowed to have two or more larvae of the corn ear worm, along with larvae fragments and the skins the worms discard as they grow.

For every ¼ cup of cornmeal, the FDA allows an average of one or more whole insects, two or more rodent hairs and 50 or more insect fragments, or one or more fragments of rodent dung.

Asparagus can contain 40 or more scary-looking but teensy thrips for every ¼ pound. If those aren’t around, FDA inspectors look for beetle eggs, entire insects or heads and body parts.

Frozen or canned spinach is allowed to have an average of 50 aphids, thrips and mites. If those are missing, the FDA allows larvae of spinach worms or eight whole leaf miner bugs.

Dismembered insects can be found in many of our favorite spices as well. Crushed oregano, for example, can contain 300 or more insect bits and about two rodent hairs for every 10 grams. To put that in context, a family-size bottle of oregano is about 18 ounces or 510 grams.

Paprika can have up to 20% mold, about 75 insect parts and 11 rodent hairs for every 25 grams (just under an ounce). A typical spice jar holds about 2 to 3 ounces.

By now you must be asking: Just how do they count those tiny insect heads and pieces of rodent dung?

“Food manufacturers have quality assurance employees who are constantly taking samples of their packaged, finished product to be sure they’re not putting anything out that is against the rules,” said food safety specialist Ben Chapman, a professor in agricultural and human sciences at North Carolina State University.

Sometimes they do it by hand, Chapman said. “They take 10 bags out of a weeklong production and try to shake out what might be in here,” he said. “Do we have particularly high insect parts or was it a particularly buggy time of year when the food was harvested? And they make sure they are below those FDA thresholds.”

What happens if it was a buggy week and lots of insects decided to sacrifice themselves? Can they get all those eggs, legs and larvae out?

“They really can’t,” Chapman said. But they can take the food and send it to a process called “rework.”

“Say I’ve got a whole bunch of buggy fresh cranberries that I can’t put in a bag and sell,” Chapman said. “I might send those to a cranberry canning operation where they can boil them and then skim those insect parts off the top and put them into a can.”

That’s gross. Will I ever eat any of these foods again?

“Look, this is all a very, very, very low-risk situation,” Chapman said. “I look at it as a yuck factor versus a risk factor. Insect parts are gross, but they don’t lead to foodborne illnesses.”

Much more dangerous, Chapman points out, is the potential for stone, metal, plastic or glass parts to come along with harvested food as it enters the processing system. All foods are subjected to X-rays and metal detectors, Chapman said, because when those slip through, people can actually be hurt.

Also much more dangerous are foodborne illnesses such as salmonella, listeria and E. coli, which can severely sicken and even kill.

“Cross-contamination from raw food, undercooking food, hand-washing and spreading germs from raw food, those are the things that contribute to the more than 48 million cases of foodborne illness we have every year in the US,” Chapman said.

Well, put that way, I guess my disgust over that rodent poop in my coffee seems overblown.

Maybe.

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25 ways to stay warm this winter that won’t break the bank | CNN

Editor’s Note: Get inspired by a weekly roundup on living well, made simple. Sign up for CNN’s Life, But Better newsletter for information and tools designed to improve your well-being.



CNN
 — 

As wintry weather whips across the United States, one challenge may be staying warm if you can’t afford or are cutting back on indoor heating.

Staying warm is necessary “for a variety of health reasons” in addition to comfort, said Dr. Georges Benjamin, the executive director of the American Public Health Association. For people with arthritis, stiffness “in your back and neck and sore joints do occur more in colder weather. … People who have metabolic conditions can be sensitive to the weather, like diabetes, for example, and heart disease. The more cold you are, the more stress you put on your heart.”

A little savvy based on our warm-blooded bodies, food, appliances, furniture, the outdoor elements and more can go a long way. Here are 25 ways to stay warm this winter — with or without indoor heating — that won’t break the bank.

How to warm your body

1. Warm up with store-bought hand warmers, microwavable heating pads, hot water bottles or heated blankets. Following the manufacturer’s instructions and concentrating on your torso are key, said JohnEric Smith, an associate professor in the department of kinesiology at Mississippi State University. “If you warm the core you can warm the hands and feet. It is harder to warm the core by warming the hands and feet.”

Be careful that you don’t burn yourself, Benjamin said. “They’re very effective on a knee or shoulder or the back of the neck. … You rarely put it directly on your skin. You usually wrap it in something, maybe a thin towel.”

2. Move your body. Physical activities like indoor exercise or dancing can help you warm up, but don’t get to the point where you’re sweating, Smith said. “We sweat to lose heat and sweating will make us colder.”

3. Think twice about taking a warm shower or bath. “While a warm bath or shower will feel good for the minute,” Smith said, “you will be cold after you get out and your wet skin is losing heat more quickly.”

4. Cuddle. Snuggles really can keep you warm. “Each of us produces heat through our metabolic processes. We lose our heat to the environment as we maintain body temperature,” Smith said via email. “Increasing skin contact decreases opportunities for the heat to be lost to the environment around us. If two people are under a blanket both of their heat losses combined can increase the temperature under the blanket more quickly than either could do independently.”

5. Change how you perceive cold. Some people have trained their minds to perceive cold as an objective, acceptable sensation rather than something dreadful to control. The best ways to adapt include wearing clothing in layers then removing it, or gradually lowering the thermostat and putting on a sweater, Benjamin said.

Enjoying warm foods and beverages is a two-in-one solution: You get heat from the appliances when you cook the food, then warmth when you eat it.

6. Enjoy warm beverages and foods, and use the oven and stove to cook them. Since foods higher in fat and protein are metabolized slowly by the body, those could make you feel warmer, Smith said. “Consider hearty soups with beans and meat.” Slow cooking meals can help generate heat throughout the day.

Drinking warm beverages “certainly helps take the chill off,” Benjamin said. Leaving the oven or stove on is “a bad idea because it burns fuel,” Benjamin said, “but more importantly, people fall asleep, they forget and leave the stove on. Sometimes things on the stove can catch on fire. So like any tool, you should use it for the purpose in which it was designed.”

“It only has to go poorly once to be life changing,” Smith said. If you don’t have children or pets, when you’re done cooking and you turn off the oven, what doesn’t hurt is leaving the oven door open to let residual heat escape.

Cozying up underneath layers of clothing or blankets (or both) can help insulate you from the cold.

7. Layer on the clothes. “Layering is critical,” Smith said. “Even thin layers added together to increase one’s ability to retain heat … focus on keeping the torso warm. Often an extra shirt or vest can warm your hands and feet more than an extra pair of socks or gloves.” Inexpensive pairs of tights or long johns can be worn underneath clothes. However, be sure that layering doesn’t make your clothing tight, he added, since that could reduce blood flow and thus your body’s ability to get warm blood to those areas. Wearing a hat, too, can also keep the heat in.

8. Wear thick socks and slippers. Fuzzy socks, slippers or a pair of shoes you reserve for wearing around the house can add extra comfort.

9. Pile on the blankets. “The more layers you put on, the better it helps trap the air between you,” your sheets and your blankets, Benjamin said. Since you lose a lot of heat from your head while you’re under blankets, he added, wearing a skull cap can help also.

10. Embrace less breathable clothing and linens. Breathable linens (such as the cotton-based variety) are often recommended during the summer, but linens with other materials and higher thread counts may be better for winter since higher thread counts have more weaving per square inch.

Optimize your home and appliances

There are multiple ways to make your heating system work better, or to create your own warmth.

11. Work with the weather. Open your curtains or blinds to let the sun in during the day, or when outside is warmer than inside your home.

12. Seal your windows and doors. Even if your windows and doors are totally shut and locked, drafts can seep in through small crevices. You can use caulk or shrink film to seal those cracks. Placing inexpensive, transparent shower curtains over windows can keep the sun in but the cold draft out. For the bottoms of doors, cloth draft stoppers are “very effective,” Benjamin said.

13. Close off unoccupied rooms. By shutting the doors of rooms no one is using, you can create additional barriers between yourself and the cold outdoors. This can also aid preventing heat loss from the room you’re in.

14. Reverse your ceiling fan. If possible, send your ceiling fan in a clockwise direction so that it sends the warm air down.

15. Sit near indoor heaters. You can safely use portable heaters if they are space heaters that have automatic shutoffs and can be plugged into a wall outlet instead of an extension cord. Since space heaters are a common cause of fires, they should be at least 3 feet away from any drapes, bedding or furniture. To prevent high levels of carbon monoxide — which can cause potentially fatal poisoning — ensure you have a carbon monoxide monitor installed and that you don’t “use any type of outdoor gas heater or anything that is not electric,” Benjamin said.

16. Move anything that’s blocking heat vents or radiators. The heat will better circulate throughout your home that way.

17. Spend time and sleep in the upper levels of the house. Heat rises, so moving your working, sleeping and living spaces upward may be more comfortable.

18. After showering, don’t run the bathroom fan or close the door. Unless your bathroom is prone to growing humidity-induced mold, the warm steam from the shower can make the nearby air less dry and cool for a short period of time.

19. Buy magnetic vent covers from home improvement stores. Used to cover vents, they can be inexpensive and help to force heat to exit vents in the occupied rooms only.

20. Put down rugs or carpets. These can be warmer to the touch than bare floors.

21. Insulate your attic. If you can afford to, padding your attic with insulation from hardware stores can help to retain some of the heat you usually lose through the attic since heat rises.

22. Research what your residential area offers. Some locations may be running warming centers set up for safety during the pandemic.

Sitting near a fire is a method that's always reliable.

23. Light a fire. If your fireplace runs on wood instead of gas, a fire is another way to keep a room warm and enjoy a cozy night. “Make sure that your flue is properly opened and clean to make sure that smoke doesn’t come back in the home but goes properly up the flue,” Benjamin said. “When the fire is out, you should of course close the flue because it’s like having an open window.”

24. Keep warm and enjoy s’mores. If your state, city, county or neighborhood allows, have a (moderate-size) backyard bonfire to keep warm for a while.

25. Don’t light candles. Candles can emit a small amount of heat, but using them as a source of warmth can be dangerous. “People will light candles and go to sleep, and they fall over,” Benjamin said. “The cat comes in and kicks it over and starts a fire.”

With these tips in mind and any others you find, be “broadly thoughtful about how to stay warm in the winter,” he added. “If it sounds like it’s a bad idea, it probably is. Look it up and check it out before you do it.”

This story has been updated to reflect recent weather advisories.

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Worried about your drinking? Use Dry January to check it | CNN

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CNN
 — 

There are lots of great reasons to decide to go “dry” in January and give up alcohol. Perhaps you imbibed a bit too much over the holidays or want to start a healthy routine and can’t afford the calories or the zap in energy and motivation that drinking can bring.

“Or it may be someone who truly is starting to wonder or question their relationship with alcohol, and this is an opportunity to really explore that,” said Dr. Sarah Wakeman, medical director of the Substance Use Disorders Initiative at Massachusetts General Hospital.

“For some people saying, ‘I’m not going to drink this entire month,’ might be really hard, so trying to do so may show you how easy or difficult it is for you,” said neuropsychologist Dr. Sanam Hafeez, who conducts classes at Columbia University’s Teachers College.

What is the advice from experts on how to have a successful “dry January”? Read on.

It helps to be clear about your goal to make it a habit, said Wakeman, an associate professor of medicine at Harvard Medical School.

“The research we have on goal setting says goals are more likely to be achieved if they’re really relevant to you as an individual and not abstract like ‘I should stop drinking because drinking is bad,’ ” she said.

Concrete goals such as embracing new sleep habits or an exercise routine will help make giving up drinking easier, she said.

“I really want to stop drinking because I know when I drink heavily I don’t get up the next morning and I don’t work out is a very specific goal,” Wakeman said.

Additional motivation can come from the health gains you can make from reducing or eliminating alcohol, experts say.

“Drinking less over time can have really measurable benefits in your health in terms of your blood pressure, your risk of cancer, your risk of liver disease and other conditions,” Wakeman said.

“Over the course of a month, you may notice some short-term benefits like better sleep, a better complexion due to improvements in your skin, feeling more clearheaded and having more energy,” she added.

READ MORE: Why my ‘Sober October’ lasted a year

Many of us may be familiar with SMART goals from work or school settings. They are used to help people set attainable goals. The acronym stands for:

  1. Specific: Set an achievable goal, such as cutting back on drinking three days a week. You can add days until you reach your final goal.
  2. Measurable: How many drinks will you cut — and what are the drink sizes? A beer is 12 ounces, a glass of wine is 5 ounces and a serving of spirits is 1.5 ounces.
  3. Achievable: Make sure there are not a bunch of social engagements where alcohol is likely to be served during your month of abstention.
  4. Relevant: How is not drinking going to help me with my life and health?
  5. Time based: Set a reasonable time frame to finish your efforts. If you like, you can set another goal later.

“If you set a bar too high, you may fail, so it’s better to set smaller goals to achieve it,” Hafeez said. “Nothing starts without an honest conversation with yourself.”

Informing a few friends or family members of your goal can help you reach it, experts say. For some people it may work to announce their plan on social media — and invite others to join in and report back on their progress.

“That’s where I think ‘dry January’ has kind of caught on,” Wakeman said. “If you publicly state you’re going to do something, you’re more likely to stick with it than if you keep it to yourself.”

READ MORE: How much you drink could have an influence on how your teen drinks

Drinking is often associated with social gatherings or fun times. That can train your brain to see alcohol as a positive. You can combat those urges by replacing your drink of choice with something equally festive or flavorful, experts say.

“For some people it can be just sparkling water, and for other people it’s actually having a mocktail or some sort of (nonalcoholic) drink that feels fun and celebratory,” Wakeman said.

“Substituting one behavior for another can work because you’re tricking your brain,” Hafeez said. “That can absolutely help you avoid temptation.”

An entire industry is devoted to making nonalcoholic drinks that taste (at least a bit) like the real thing. Some even claim to have added ingredients that are “calming” or “healthy.”

“I’m skeptical of anything that claims to relax you or have amazing health benefits that comes in a glass regardless of what it is,” Wakeman said. “But if it’s an alternative that allows you to feel like you’re not missing out on a social situation and helps you make the changes that you want to your alcohol consumption, I don’t think there’s any downside to that.”

READ MORE: How to stop using alcohol as a confidence crutch

5. Track your progress, goal and feelings

Even if you don’t end up cutting out all alcohol, tracking your emotions and urges to discover your triggers can be helpful, Wakeman said.

“Even just measuring your behavior, whether it’s alcohol or exercise or your diet, can be an intervention in and of itself,” she said.

“Even if someone’s not yet ready to make changes, just keeping a diary of when you’re drinking, what situations you’re drinking more and how you’re feeling at those times, can really help you identify sort of trigger situations where you may be more likely to drink,” Wakeman added.

There’s an additional piece that’s important in accomplishing a “dry January,” experts say. It’s important to notice if you — or a loved one — are showing any negative symptoms from cutting back or eliminating alcohol. It could be a sign that you need professional help to reach your goal.

“The first thing to be mindful of is whether or not you actually have an alcohol use disorder,” Wakeman said. “If someone’s been drinking very heavily ev

ery single day and is at risk for withdrawal symptoms, then it can actually be dangerous to stop abruptly.”

A person with an alcohol use disorder, who has gotten used to having a certain level of alcohol in their body every day, can go into withdrawal and experience severe physical symptoms such as shakiness, sweating, rapid heart rate and seizures.

“That would be a real indication that you need to talk to a medical professional about getting medical treatment for withdrawal and not stopping on your own,” Wakeman said.

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No antibiotics worked, so this woman turned to a natural enemy of bacteria to save her husband’s life | CNN



CNN
 — 

In February 2016, infectious disease epidemiologist Steffanie Strathdee was holding her dying husband’s hand, watching him lose an exhausting fight against a deadly superbug infection.

After months of ups and downs, doctors had just told her that her husband, Tom Patterson, was too racked with bacteria to live.

“I told him, ‘Honey, we’re running out of time. I need to know if you want to live. I don’t even know if you can hear me, but if you can hear me and you want to live, please squeeze my hand.’

“All of a sudden, he squeezed really hard. And I thought, ‘Oh, great!’ And then I’m thinking, ‘Oh, crap! What am I going to do?’”

What she accomplished next could easily be called miraculous. First, Strathdee found an obscure treatment that offered a glimmer of hope — fighting superbugs with phages, viruses created by nature to eat bacteria.

Then she convinced phage scientists around the country to hunt and peck through molecular haystacks of sewage, bogs, ponds, the bilge of boats and other prime breeding grounds for bacteria and their viral opponents. The impossible goal: quickly find the few, exquisitely unique phages capable of fighting a specific strain of antibiotic-resistant bacteria literally eating her husband alive.

Next, the US Food and Drug Administration had to greenlight this unproven cocktail of hope, and scientists had to purify the mixture so that it wouldn’t be deadly.

Yet just three weeks later, Strathdee watched doctors intravenously inject the mixture into her husband’s body — and save his life.

Their story is one of unrelenting perseverance and unbelievable good fortune. It’s a glowing tribute to the immense kindness of strangers. And it’s a story that just might save countless lives from the growing threat of antibiotic-resistant superbugs — maybe even your own.

“It’s estimated that by 2050, 10 million people per year — that’s one person every three seconds — is going to be dying from a superbug infection,” Strathdee told an audience at Life Itself, a 2022 health and wellness event presented in partnership with CNN.

“I’m here to tell you that the enemy of my enemy can be my friend. Viruses can be medicine.”

sanjay pkg vpx

How this ‘perfect predator’ saved his life after nine months in the hospital

During a Thanksgiving cruise on the Nile in 2015, Patterson was suddenly felled by severe stomach cramps. When a clinic in Egypt failed to help his worsening symptoms, Patterson was flown to Germany, where doctors discovered a grapefruit-size abdominal abscess filled with Acinetobacter baumannii, a virulent bacterium resistant to nearly all antibiotics.

Found in the sands of the Middle East, the bacteria were blown into the wounds of American troops hit by roadside bombs during the Iraq War, earning the pathogen the nickname “Iraqibacter.”

“Veterans would get shrapnel in their legs and bodies from IED explosions and were medevaced home to convalesce,” Strathdee told CNN, referring to improvised explosive devices. “Unfortunately, they brought their superbug with them. Sadly, many of them survived the bomb blasts but died from this deadly bacterium.”

Today, Acinetobacter baumannii tops the World Health Organization’s list of dangerous pathogens for which new antibiotics are critically needed.

“It’s something of a bacterial kleptomaniac. It’s really good at stealing antimicrobial resistance genes from other bacteria,” Strathdee said. “I started to realize that my husband was a lot sicker than I thought and that modern medicine had run out of antibiotics to treat him.”

With the bacteria growing unchecked inside him, Patterson was soon medevaced to the couple’s hometown of San Diego, where he was a professor of psychiatry and Strathdee was the associate dean of global health sciences at the University of California, San Diego.

“Tom was on a roller coaster — he’d get better for a few days, and then there would be a deterioration, and he would be very ill,” said Dr. Robert “Chip” Schooley, a leading infectious disease specialist at UC San Diego who was a longtime friend and colleague. As weeks turned into months, “Tom began developing multi-organ failure. He was sick enough that we could lose him any day.”

Patterson's body was systemically infected with a virulent drug-resistant bacteria that also infected troops in the Iraq War, earning the pathogen the nickname

After that reassuring hand squeeze from her husband, Strathdee sprang into action. Scouring the internet, she had already stumbled across a study by a Tbilisi, Georgia, researcher on the use of phages for treatment of drug-resistant bacteria.

A phone call later, Strathdee discovered phage treatment was well established in former Soviet bloc countries but had been discounted long ago as “fringe science” in the West.

“Phages are everywhere. There’s 10 million trillion trillion — that’s 10 to the power of 31 — phages that are thought to be on the planet,” Strathdee said. “They’re in soil, they’re in water, in our oceans and in our bodies, where they are the gatekeepers that keep our bacterial numbers in check. But you have to find the right phage to kill the bacterium that is causing the trouble.”

Buoyed by her newfound knowledge, Strathdee began reaching out to scientists who worked with phages: “I wrote cold emails to total strangers, begging them for help,” she said at Life Itself.

One stranger who quickly answered was Texas A&M University biochemist Ryland Young. He’d been working with phages for over 45 years.

“You know the word persuasive? There’s nobody as persuasive as Steffanie,” said Young, a professor of biochemistry and biophysics who runs the lab at the university’s Center for Phage Technology. “We just dropped everything. No exaggeration, people were literally working 24/7, screening 100 different environmental samples to find just a couple of new phages.”

While the Texas lab burned the midnight oil, Schooley tried to obtain FDA approval for the injection of the phage cocktail into Patterson. Because phage therapy has not undergone clinical trials in the United States, each case of “compassionate use” required a good deal of documentation. It’s a process that can consume precious time.

But the woman who answered the phone at the FDA said, “‘No problem. This is what you need, and we can arrange that,’” Schooley recalled. “And then she tells me she has friends in the Navy that might be able to find some phages for us as well.”

In fact, the US Naval Medical Research Center had banks of phages gathered from seaports around the world. Scientists there began to hunt for a match, “and it wasn’t long before they found a few phages that appeared to be active against the bacterium,” Strathdee said.

Dr. Robert

Back in Texas, Young and his team had also gotten lucky. They found four promising phages that ravaged Patterson’s antibiotic-resistant bacteria in a test tube. Now the hard part began — figuring out how to separate the victorious phages from the soup of bacterial toxins left behind.

“You put one virus particle into a culture, you go home for lunch, and if you’re lucky, you come back to a big shaking, liquid mess of dead bacteria parts among billions and billions of the virus,” Young said. “You want to inject those virus particles into the human bloodstream, but you’re starting with bacterial goo that’s just horrible. You would not want that injected into your body.”

Purifying phage to be given intravenously was a process that no one had yet perfected in the US, Schooley said, “but both the Navy and Texas A&M got busy, and using different approaches figured out how to clean the phages to the point they could be given safely.”

More hurdles: Legal staff at Texas A&M expressed concern about future lawsuits. “I remember the lawyer saying to me, ‘Let me see if I get this straight. You want to send unapproved viruses from this lab to be injected into a person who will probably die.’ And I said, “Yeah, that’s about it,’” Young said.

“But Stephanie literally had speed dial numbers for the chancellor and all the people involved in human experimentation at UC San Diego. After she calls them, they basically called their counterparts at A&M, and suddenly they all began to work together,” Young added.

“It was like the parting of the Red Sea — all the paperwork and hesitation disappeared.”

The purified cocktail from Young’s lab was the first to arrive in San Diego. Strathdee watched as doctors injected the Texas phages into the pus-filled abscesses in Patterson’s abdomen before settling down for the agonizing wait.

“We started with the abscesses because we didn’t know what would happen, and we didn’t want to kill him,” Schooley said. “We didn’t see any negative side effects; in fact, Tom seemed to be stabilizing a bit, so we continued the therapy every two hours.”

Two days later, the Navy cocktail arrived. Those phages were injected into Patterson’s bloodstream to tackle the bacteria that had spread to the rest of his body.

“We believe Tom was the first person to receive intravenous phage therapy to treat a systemic superbug infection in the US,” Strathdee told CNN.

“And three days later, Tom lifted his head off the pillow out of a deep coma and kissed his daughter’s hand. It was just miraculous.”

Patterson awoke from a coma after receiving an intravenous dose of phages tailored to his bacteria.

Today, nearly eight years later, Patterson is happily retired, walking 3 miles a day and gardening. But the long illness took its toll: He was diagnosed with diabetes and is now insulin dependent, with mild heart damage and gastrointestinal issues that affect his diet.

“He isn’t back surfing again, because he can’t feel the bottoms of his feet, and he did get Covid-19 in April that landed him in the hospital because the bottoms of his lungs are essentially dead,” Strathdee said.

“As soon as the infection hit his lungs he couldn’t breathe and I had to rush him to the hospital, so that was scary,” she said. “He remains high risk for Covid but we’re not letting that hold us hostage at home. He says, ‘I want to go back to having as normal life as fast as possible.’”

To prove it, the couple are again traveling the world — they recently returned from a 12-day trip to Argentina.

“We traveled with a friend who is an infectious disease doctor, which gave me peace of mind to know that if anything went sideways, we’d have an expert at hand,” Strathdee said.

“I guess I’m a bit of a helicopter wife in that sense. Still, we’ve traveled to Costa Rica a couple of times, we’ve been to Africa, and we’re planning to go to Chile in January.”

Patterson’s case was published in the journal Antimicrobial Agents and Chemotherapy in 2017, jump-starting new scientific interest in phage therapy.

“There’s been an explosion of clinical trials that are going on now in phage (science) around the world and there’s phage programs in Canada, the UK, Australia, Belgium, Sweden, Switzerland, India and China has a new one, so it’s really catching on,” Strathdee told CNN.

Some of the work is focused on the interplay between phages and antibiotics — as bacteria battle phages they often shed their outer shell to keep the enemy from docking and gaining access for the kill. When that happens, the bacteria may be suddenly vulnerable to antibiotics again.

“We don’t think phages are ever going to entirely replace antibiotics, but they will be a good adjunct to antibiotics. And in fact, they can even make antibiotics work better,” Strathdee said.

In San Diego, Strathdee and Schooley opened the Center for Innovative Phage Applications and Therapeutics, or IPATH, in 2018, where they treat or counsel patients suffering from multidrug-resistant infections. The center’s success rate is high, with 82% of patients undergoing phage therapy experiencing a clinically successful outcome, according to its website.

Schooley is running a clinical trial using phages to treat patients with cystic fibrosis who constantly battle Pseudomonas aeruginosa, a drug-resistant bacteria that was also responsible for the recent illness and deaths connected to contaminated eye drops manufactured in India.

And a memoir the couple published in 2019 — “The Perfect Predator: A Scientist’s Race to Save Her Husband From a Deadly Superbug” — is also spreading the word about these “perfect predators” to what may soon be the next generation of phage hunters.

VS Phages Sanjay Steffanie

How naturally occurring viruses could help treat superbug infections

“I am getting increasingly contacted by students, some as young as 12,” Strathdee said. “There’s a girl in San Francisco who begged her mother to read this book and now she’s doing a science project on phage-antibiotic synergy, and she’s in eighth grade. That thrills me.”

Strathdee is quick to acknowledge the many people who helped save her husband’s life. But those who were along for the ride told CNN that she and Patterson made the difference.

“I think it was a historical accident that could have only happened to Steffanie and Tom,” Young said. “They were at UC San Diego, which is one of the premier universities in the country. They worked with a brilliant infectious disease doctor who said, ‘Yes,’ to phage therapy when most physicians would’ve said, ‘Hell, no, I won’t do that.’

“And then there is Steffanie’s passion and energy — it’s hard to explain until she’s focused it on you. It was like a spiderweb; she was in the middle and pulled on strings,” Young added. “It was just meant to be because of her, I think.”

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Don’t serve disordered eating to your teens this holiday season | CNN

Editor’s Note: Katie Hurley, author of “No More Mean Girls: The Secret to Raising Strong, Confident and Compassionate Girls,” is a child and adolescent psychotherapist in Los Angeles. She specializes in work with tweens, teens and young adults.



CNN
 — 

“I have a couple of spots for anyone who wants to lose 20 pounds by the holidays! No diets, exercise, or cravings!”

Ads for dieting and exercise programs like this started appearing in my social media feeds in early October 2022, often accompanied by photos of women pushing shopping carts full of Halloween candy intended to represent the weight they no longer carry with them.

Whether it’s intermittent fasting or “cheat” days, diet culture is spreading wildly, and spiking in particular among young women and girls, a population group who might be at particular risk of social pressures and misinformation.

The fact that diet culture all over social media targets grown women is bad enough, but such messaging also trickles down to tweens and teens. (And let’s be honest, a lot is aimed directly at young people too.) It couldn’t happen at a worse time: There’s been a noticeable spike in eating disorders, particularly among adolescent girls, since the beginning of the pandemic.

“My mom is obsessed with (seeing) her Facebook friends losing tons of weight without dieting. Is this even real?” The question came from a teen girl who later revealed she was considering hiring a health coach to help her eat ‘healthier’ after watching her mom overhaul her diet. Sadly, the coaching she was falling victim to is part of a multilevel marketing brand that promotes quick weight loss through caloric restriction and buying costly meal replacements.

Is it real? Yes. Is it healthy? Not likely, especially for a growing teen.

Later that week, a different teen client asked about a clean eating movement she follows on Pinterest. She had read that a strict clean vegan diet is better for both her and the environment, and assumed this was true because the pinned article took her to a health coaching blog. It seemed legitimate. But a deep dive into the blogger’s credentials, however, showed that the clean eating practices they shared were not actually developed by a nutritionist.

And another teen, fresh off a week of engaging in the “what I eat in a day” challenge — a video trend across TikTok, Instagram and other social media platforms where users document the food they consume in a particular timeframe — told me she decided to temporarily mute her social media accounts. Why? Because the time she’d spent limited her eating while pretending to feel full left her exhausted and unhappy. She had found the trend on TikTok and thought it might help her create healthier eating habits, but ended up becoming fixated on caloric intake instead. Still, she didn’t want her friends to see that the challenge actually made her feel terrible when she had spent a whole week promoting it.

During any given week, I field numerous questions from tweens and teens about the diet culture they encounter online, out in the world, and sometimes even in their own homes. But as we enter the winter holiday season, shame-based diet culture pressure, often wrapped up with toxic positivity to appear encouraging, increases.

“As we approach the holidays, diet culture is in the air as much as lights and music, and it’s certainly on social media,” said Dr. Hina Talib, an adolescent medicine specialist and associate professor of pediatrics at the Albert Einstein College of Medicine in The Bronx, New York. “It’s so pervasive that even if it’s not targeted (at) teens, they are absorbing it by scrolling through it or hearing parents talk about it.”

Social media isn’t the only place young people encounter harmful messaging about body image and weight loss. Teens are inundated with so-called ‘healthy eating’ content on TV and in popular culture, at school and while engaged in extracurricular or social activities, at home and in public spaces like malls or grocery stores — and even in restaurants.

Instead of learning how to eat to fuel their bodies and their brains, today’s teens are getting the message that “clean eating,” to give just one example of a potentially problematic dietary trend, results in a better body — and, by extension, increased happiness. Diets cutting out all carbohydrates, dairy products, gluten, and meat-based proteins are popular among teens. Yet this mindset can trigger food anxiety, obsessive checking of food labels and dangerous calorie restriction.

An obsessive focus on weight loss, toning muscles and improving overall looks actually runs contrary to what teens need to grow at a healthy pace.

“Teens and tweens are growing into their adult bodies, and that growth requires weight gain,” said Oona Hanson, a parent coach based in Los Angeles. “Weight gain is not only normal but essential for health during adolescence.”

The good news in all of this is that parents can take an active role in helping teens craft an emotionally healthier narrative around their eating habits. “Parents are often made to feel helpless in the face of TikTokers, peer pressure or wider diet culture, but it’s important to remember this: parents are influencers, too,” said Hanson. What we say and do matters to our teens.

Parents can take an active role in helping teens craft an emotionally healthier narrative around their eating habits.

Take a few moments to reflect on your own eating patterns. Teens tend to emulate what they see, even if they don’t talk about it.

Parents and caregivers can model a healthy relationship with food by enjoying a wide variety of foods and trying new recipes for family meals. During the holiday season, when many celebrations can involve gathering around the table, take the opportunity to model shared connections. “Holidays are a great time to remember that foods nourish us in ways that could never be captured on a nutrition label,” Hanson said.

Practice confronting unhealthy body talk

The holiday season is full of opportunities to gather with friends and loved ones to celebrate and make memories, but these moments can be anxiety-producing when nutrition shaming occurs.

When extended families gather for holiday celebrations, it’s common for people to comment on how others look or have changed since the last gathering. While this is usually done with good intentions, it can be awkward or upsetting to tweens and teens.

“For young people going through puberty or body changes, it’s normal to be self-conscious or self-critical. To have someone say, ‘you’ve developed’ isn’t a welcome part of conversations,” cautioned Talib.

Talib suggests practicing comebacks and topic changes ahead of time. Role play responses like, “We don’t talk about bodies,” or “We prefer to focus on all the things we’ve accomplished this year.” And be sure to check in and make space for your tween or teen to share and feelings of hurt and resentment over any such comments at an appropriate time.

Open and honest communication is always the gold standard in helping tweens and teens work through the messaging and behaviors they internalize. When families talk about what they see and hear online, on podcasts, on TV, and in print, they normalize the process of engaging in critical thinking — and it can be a really great shared connection between parents and teens.

“Teaching media literacy skills is a helpful way to frame the conversation,” says Talib. “Talk openly about it.”

She suggests asking the following questions when discussing people’s messaging around diet culture:

● Who are they?

● What do you think their angle is?

● What do you think their message is?

● Are they a medical professional or are they trying to sell you something?

● Are they promoting a fitness program or a supplement that they are marketing?

Talking to tweens and teens about this throughout the season — and at any time — brings a taboo topic to the forefront and makes it easier for your kids to share their inner thoughts with you.

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Scientists finally know why people get more colds and flu in winter | CNN

Editor’s Note: Get inspired by a weekly roundup on living well, made simple. Sign up for CNN’s Life, But Better newsletter for information and tools designed to improve your well-being.



CNN
 — 

There’s a chill is in the air, and you all know what that means — it’s time for cold and flu season, when it seems everyone you know is suddenly sneezing, sniffling or worse. It’s almost as if those pesky cold and flu germs whirl in with the first blast of winter weather.

Yet germs are present year-round — just think back to your last summer cold. So why do people get more colds, flu and now Covid-19 when it’s chilly outside?

In what they called a “breakthrough,” scientists uncovered the biological reason we get more respiratory illnesses in winter — the cold air itself damages the immune response occurring in the nose.

“This is the first time that we have a biologic, molecular explanation regarding one factor of our innate immune response that appears to be limited by colder temperatures,” said rhinologist Dr. Zara Patel, a professor of otolaryngology and head and neck surgery at Stanford University School of Medicine in California. She was not involved in the new study.

In fact, reducing the temperature inside the nose by as little as 9 degrees Fahrenheit (5 degrees Celsius) kills nearly 50% of the billions of helpful bacteria-fighting cells and viruses in the nostrils, according to the 2022 study published in The Journal of Allergy and Clinical Immunology.

“Cold air is associated with increased viral infection because you’ve essentially lost half of your immunity just by that small drop in temperature,” said study author Dr. Benjamin Bleier, director of otolaryngology translational research at Massachusetts Eye and Ear and an associate professor at Harvard Medical School in Boston.

“it’s important to remember that these are in vitro studies, meaning that although it is using human tissue in the lab to study this immune response, it is not a study being carried out inside someone’s actual nose,” Patel said in an email. “Often the findings of in vitro studies are confirmed in vivo, but not always.”

To understand why this occurs, Bleier and his team and coauthor Mansoor Amiji, who chairs the department of pharmaceutical sciences at Northeastern University in Boston, went on a scientific detective hunt.

A respiratory virus or bacteria invades the nose, the main point of entry into the body. Immediately, the front of the nose detects the germ, well before the back of the nose is aware of the intruder, the team discovered.

At that point, cells lining the nose immediately begin creating billions of simple copies of themselves called extracellular vesicles, or EV’s.

“EV’s can’t divide like cells can, but they are like little mini versions of cells specifically designed to go and kill these viruses,” Bleier said. “EV’s act as decoys, so now when you inhale a virus, the virus sticks to these decoys instead of sticking to the cells.”

Those “Mini Me’s” are then expelled by the cells into nasal mucus (yes, snot), where they stop invading germs before they can get to their destinations and multiply.

“This is one of, if not the only part of the immune system that leaves your body to go fight the bacteria and viruses before they actually get into your body,” Bleier said.

Once created and dispersed out into nasal secretions, the billions of EV’s then start to swarm the marauding germs, Bleier said.

“It’s like if you kick a hornet’s nest, what happens? You might see a few hornets flying around, but when you kick it, all of them all fly out of the nest to attack before that animal can get into the nest itself,” he said. “That’s the way the body mops up these inhaled viruses so they can never get into the cell in the first place.”

READ MORE: Is it a cold, flu or Covid-19? A doctor helps sort it out

When under attack, the nose increases production of extracellular vesicles by 160%, the study found. There were additional differences: EV’s had many more receptors on their surface than original cells, thus boosting the virus-stopping ability of the billions of extracellular vesicles in the nose.

“Just imagine receptors as little arms that are sticking out, trying to grab on to the viral particles as you breathe them in,” Bleier said. “And we found each vesicle has up to 20 times more receptors on the surface, making them super sticky.”

Cells in the body also contain a viral killer called micro RNA, which attack invading germs. Yet EVs in the nose contained 13 times micro RNA sequences than normal cells, the study found.

So the nose comes to battle armed with some extra superpowers. But what happens to those advantages when cold weather hits?

To find out, Bleier and his team exposed four study participants to 15 minutes of 40-degree-Fahrenheit (4.4-degree-Celsius) temperatures, and then measured conditions inside their nasal cavities.

“What we found is that when you’re exposed to cold air, the temperature in your nose can drop by as much as 9 degrees Fahrenheit. And that’s enough to essentially knock out all three of those immune advantages that the nose has,” Bleier said.

In fact, that little bit of coldness in the tip of the nose was enough to take nearly 42% of the extracellular vesicles out of the fight, Bleier said.

“Similarly, you have almost half the amount of those killer micro RNA’s inside each vesicle, and you can have up to a 70% drop in the number of receptors on each vesicle, making them much less sticky,” he said.

What does that do to your ability to fight off colds, flu and Covid-19? It cuts your immune system’s ability to fight off respiratory infections by half, Bleier said.

READ MORE: Why people who qualify should get the RSV vaccine

As it turns out, the pandemic gave us exactly what we need to help fight off chilly air and keep our immunity high, Bleier said.

“Not only do masks protect you from the direct inhalation of viruses, but it’s also like wearing a sweater on your nose,” he said.

Patel agreed: “The warmer you can keep the intranasal environment, the better this innate immune defense mechanism will be able to work. Maybe yet another reason to wear masks!”

In the future, Bleier expects to see the development of topical nasal medications that build upon this scientific revelation. These new pharmaceuticals will “essentially fool the nose into thinking it has just seen a virus,” he said.

“By having that exposure, you’ll have all these extra hornets flying around in your mucous protecting you,” he added.

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How to fix your job so that you love it, in three steps | CNN

Editor’s Note: This essay is part of a column called The Wisdom Project.



CNN
 — 

More than a third of American find their job unsatisfactory, according to an annual survey by the Conference Board research group. From 2000 to 2016, the nation had been hovering around the halfway mark of job dissatisfaction.

That statistic means three or four of every 10 people you work with every day are living a work life that Henry David Thoreau would have described as one of “quiet desperation.”

Many of us also unhelpfully conflate our self-worth with our career. Our job unhappiness becomes life unhappiness, which raises the stakes.

Wouldn’t it be nice to stop being envious of those who love their jobs and become one of those people?

There is a lot of career advice out there about how to ask for a raise, get a promotion, deal with a difficult boss, manage others and so on. But very little addresses the fundamental issue of your day-to-day happiness at work.

The factors that can tip the scales one way or the other for job happiness can boil down to our innate desire for three things: control over our lives, positive daily connections, and joy and meaning in how we spend our waking time (half of which is at work, for most people).

The way to integrate our need for control, connection and meaning — while on the clock — is by “job crafting.” That’s the term used by Yale University psychologist Amy Wrzesniewski and University of Michigan professor of business administration and psychology Jane E. Dutton. It’s about “taking control of, or reframing, some of these factors,” they wrote in a study on the topic.

People who don’t like their jobs — i.e., the majority of us — may suffer and grumble day to day. They may even be chronically stressed, a state that has serious medical consequences, including hypertension, cardiovascular disease and decreased mental health, according to a meta-analysis of studies by the Stanford Graduate School of Business and Harvard Business School.

There are also factors connected to job happiness that we have little control over, such as your boss. About half of people who quit their job did so “to get away from their manager,” according to a recent Gallup poll. Salaries are important as well.

But we don’t usually decide who our boss is, and they can suddenly change (for good or bad). As for money, studies have shown it has only a short-term effect on happiness.

So that leaves you with one powerful recourse: Take matters into your own hands.

Wrzesniewski and Dutton’s research focused on three main factors of deeper workplace satisfaction that are within your sphere of influence: 1) Refining your job to add parts you like and remove parts you don’t. 2) Building better relationships with your colleagues. 3) Reframing your job to add meaning and purpose.

Wrzesniewski distilled them nicely on the excellent social science podcast The Hidden Brain. Their research isn’t just theoretical. They wrote an instruction manual on how to job craft.

And — in my own, less scientific, more DIY way — here are exercises I’ve been practicing to get into better work happiness shape.

Start by making three lists. (Do this over a nice cup of coffee or tea in a quiet place, during work hours, even if it’s in your own living room.) One list is all the things you currently like about your job, big and small. The second lists all the hassles and headaches of your job, from the petty to the systemic.

And the third lists things you’d like to be able to do in your job that you currently don’t — even if they have nothing to do with what you’re paid to do. You can add “take more solo brainstorming coffee breaks” to it if you like.

Now, it’s time to systematically attack items on the second two lists. Go for a few easy wins first. Some things you can start adding and subtracting today; others may take months. Some may require buy-in from your boss (who will hopefully be amenable to increasing your workplace happiness), but many won’t. Some changes will be directly related to your job, while others will just be ways to increase happiness or reduce stress while there.

It’s all progress.

Be imaginative with these lists. Creativity is itself a well-being booster. Writing this wisdom column is something I added to my job. It has benefits to the company I can easily articulate but also makes me happy (and adds meaning to my job). I also try to work in exercise during the work day, running during lunch or during a meeting where I just have to listen in. Again, it has the benefit of reducing stress and sick days while increasing my energy at work but also benefits me personally.

Over time, your lists will grow and, as you cross off items, shrink. But make sure that when you remove an item from the second list (things you don’t like) and third list (what you want to add), you record the change on the first list (things you like about your job). Every new item on that first list is another rung in the ladder of work happiness, and it’s good to look down every so often and see how high you’ve reached.

You can’t do much to change the cast of characters with whom you work. But you can enhance every one of those relationships.

Learn more about what others want and help them achieve it, even if you aren’t their boss. Make meetings more fun or engaging. Help reduce the length, mandatory attendance and frequency of those meetings. Try inserting humor throughout the day.

Just getting to know your colleagues better — which is no harder than asking them questions — deepens your connection to them. The more you’re connected, the more you’re going to look forward to working with them every day. And if you look forward to interacting with your coworkers, you’re going to like your job a lot more as a result. You may not like what you do, but at least Michael, Jamie, Collin, Fiona and Saeed will be there!

The added benefit of this second effort is that it increases happiness for your colleagues too, perhaps helping them to tip their scale into the “satisfactory” side and beyond.

Wrzesniewski and Dutton’s research focused, in part, on a group of hospital cleaning staff. It’s a job that most people, without having done it, might assume would be unsatisfactory. Cleaning bed pans and interacting with the sick and dying is few people’s dream job.

But what they found was that a significant factor among those who reported liking their job was how they cognitively reframed it. The work was the same for everyone, but while some thought it was comprised of uncreative tasks, those who liked the work thought of themselves as playing a critical role in healing patients. One hospital worker considered themselves an “ambassador.”

And it’s not just thinking differently, because that has limited effect when nothing else changes. Thinking differently altered the way they performed the job, as well.

“It’s more than just a change of mindset,” Wrzesniewski explained to me. “It’s a change in your behavior approach to your job. If you think ‘I’m an ambassador to the hospital,’ it changes what you do.”

For example, you may be cleaning bedpans, but if you think of yourself as a caregiver, you may be looking at what’s in the bedpan for signs of health problems to alert to a nurse. “You don’t think, ‘I can’t do that,’” said Wrzesniewski. “That’s where the action really comes in.”

By shifting the paradigm around their job and adding meaning and purpose, the hospital staff made the tougher parts of their job tolerable, even important, and changed their behavior to support that purpose.

Can you do that with your job?

Think about the part you play in a larger framework that has a positive effect on others, or culture, or the environment. You may do data entry in a cubicle, but what’s that data used for? And how is your commitment to accuracy and detail vital to the effectiveness of that data? You may perform rote tasks in a factory, but are you helping build something that people need or brings others joy?

How might your actions change when you start seeing it that way?

Beyond whatever the job itself accomplishes, there is also meaning and purpose with what you do with your wages. Providing for your family, for example, is fundamentally important to their ability to thrive. It is important — particularly when you are stressed, put out or otherwise unhappy — to remind yourself of the security and opportunities garnered from your wages. That alone may give you strength in difficult moments at work.

“Onboarding” is the term human resources folks use when someone starts at a new company, to get them prepared.

It’s now time for you to get on board with your new start. You’re prepared. You are the human resource you’ve been waiting for.

Here’s the last takeaway: These factors — improving how you spend time, connecting with those around you, adding meaning to your tasks — are just as vital for your non-working hours.

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Urinary tract infections in men: Here are 10 things to know | CNN

Editor’s Note: Dr. Jamin Brahmbhatt is a urologist and robotic surgeon with Orlando Health and president of the Florida Urological Society.



CNN
 — 

While urinary tract infections are more common in women, men can still get what’s commonly known as a UTI. Here are 10 things I’d like you to know about urinary tract infections, including who’s more at risk and how to get treatment.

UTI is short for urinary tract infection. It’s an infection of the organs in your body – I call them pipes – that are meant to funnel your urine out of your system and into the urinal. Most UTIs are caused by bacteria that work their way into the urethra, prostate, bladder or kidneys.

Way more women than men are diagnosed with UTIs. Anatomically, we feel this happens because women have a shorter urethra – the tube that connects the bladder to the outside world. The shorter length makes it easier for bacteria to travel to the urinary system. Men have longer urethras and therefore can be protected against urinary infections.

But the length of the urethra alone cannot protect men against UTIs – over their lifetimes, 12% of men will get urinary symptoms linked to a UTI. This by no means implies a urethra or penis are short or small. In men, there is usually a more clear pathologic cause to the infection beyond just the length of the urethra.

There are many reasons why a guy may get a UTI – all of them we take seriously and should not be ignored.

Men older than 50 tend to get more infections than younger men. As a urologist, I see men get recurrent infections when they do not properly empty their bladder because of an enlarged prostate. Beyond the prostate, men may not empty their bladder if they have nerve damage from stroke, uncontrolled diabetes or injury to the spine.

Men can also get infections that start from the prostate or testicles that seed up into the bladder, or the opposite can happen where the infection goes from the bladder to the other organs. Kidney stones can also be a cause of infection. (I know this from personal experience – I’ve had a kidney stone myself!)

Younger men may also present with urinary infections because of sexually transmitted diseases. Men can also get an infection if they have a recent procedure done in the urinary system.

4. What are the signs and symptoms of a UTI?

Burning with urination (dysuria), increased urinary frequency, urgency, incontinence, foul smell, blood in the urine, fevers, chills, pain in the abdomen near the bladder. Believe it or not, some men may have zero symptoms and still get diagnosed with a UTI based on urine cultures done for other purposes.

UTI is diagnosed by sending your urine off for a culture. This is when a sample of your urine is processed and evaluated for various strains of bacteria. The most common bacteria identified in urinary tract infections is E.coli. Once the culture is done, the results can guide treatment, which is usually oral antibiotics. There is a test called a urine analysis which can be done quickly in our office which can suggest an infection. However, the best test is an actual culture.

Doctors do not wait for the culture results – which can take one to three days – to start treatment. If an infection is suspected, an antibiotic will be started immediately and then adjusted based on the culture results.

UTIs generally are treated with oral or IV antibiotics. Most infections can be treated with oral antibiotics. However there are superbugs that may be resistant to what we can give you by mouth that may require the use of stronger antibiotics through an IV. Most treatments last seven to 10 days, but can be longer.

In severe cases of infection that has spread to the bloodstream, strong IV antibiotics are started immediately to control the infection. Patients are placed in the hospital to start these strong treatments. You do not have to stay in the hospital for weeks if you have infection in your bloodstream. As long as you are doing well – no fever, normal labs, heart and pulse OK – then you may continue these IV treatments from home. Each treatment is tailored to your condition.

As a doctor, my answer is: No. Men should not try to treat infections on their own. If you have symptoms, get yourself to a doctor or emergency room.

The best prevention is making sure first there is nothing anatomical that needs to be corrected, such as an enlarged prostate, kidney stone or blockage.

Proper hygiene can help prevent infections. Men with uncircumcised penises should make sure they can retract the foreskin and clean under the foreskin and the glans properly. Cranberry supplements have been shown to help prevent infections. Staying hydrated by drinking enough fluids/water during the day can also help. Making sure you don’t hold your urine can help, too. Staying in good health to avoid chronic medical conditions such as diabetes and heart disease will also protect against infections.

9. My infection is gone. Are there any long-term effects on my body?

Recurrent, untreated infections could cause strictures, or tight scars, in your urethra that would slow your stream and make it difficult to empty your bladder. Infections could also cause the bladder to lose its ability to fill and empty properly. In the long run, if you are getting constantly treated with antibiotics, we may run out of antibiotics to give you due to resistance.

The first priority is to clear the infection with antibiotics.

From there, we do a full workup with a detailed history, evaluation of chronic medical problems and exam of the genitals to look for anatomic issues such as a foreskin that won’t retract back. Imaging may include a CT scan of the abdomen and pelvis to look for kidney stones, blocked tubes and other abnormalities.

If you see a urologist, you will likely get a cystoscopy, where we place a camera inside of a small tube into the urethra to look at the inside of your urine channel. The cystoscopy helps look for strictures, large obstructing prostates and changes to the bladder walls. Once a cause is found, it’s aggressively treated with either medication or surgery.

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Nearly two years after Texas’ six-week abortion ban, more infants are dying | CNN



CNN
 — 

Texas’ abortion restrictions – some of the strictest in the country – may be fueling a sudden spike in infant mortality as women are forced to carry nonviable pregnancies to term.

Some 2,200 infants died in Texas in 2022 – an increase of 227 deaths, or 11.5%, over the previous year, according to preliminary infant mortality data CNN obtained through a public records request. Infant deaths caused by severe genetic and birth defects rose by 21.6%. That spike reversed a nearly decade-long decline. Between 2014 and 2021, infant deaths had fallen by nearly 15%.

In 2021, Texas banned abortions beyond six weeks of pregnancy. When the Supreme Court overturned federal abortion rights the following summer, a trigger law in the state banned all abortions other than those intended to protect the life of the mother.

The increase in deaths could partly be explained by the fact that more babies are being born in Texas. One recent report found that in the final nine months of 2022, the state saw nearly 10,000 more births than expected prior to its abortion ban – an estimated 3% increase.

But multiple obstetrician-gynecologists who focus on high-risk pregnancies told CNN that Texas’ strict abortion laws likely contributed to the uptick in infant deaths.

“We all knew the infant mortality rate would go up, because many of these terminations were for pregnancies that don’t turn into healthy normal kids,” said Dr. Erika Werner, the chair of obstetrics and gynecology at Tufts Medical Center. “It’s exactly what we all were concerned about.”

The issue of forcing women to carry out terminal and often high-risk pregnancies is at the core of a lawsuit filed by the Center for Reproductive Rights, with several women – who suffered difficult pregnancies or infant deaths shortly after giving birth – testifying in Travis County court this week.

Prior to the recent abortion restrictions, Texas banned the procedure after 20 weeks. This law gave parents more time to learn crucial information about a fetus’s brain formation and organ development, which doctors begin to test for at around 15 weeks.

Samantha Casiano, a plaintiff in the suit filed against Texas, wished she’d had more time to make the decision.

“If I was able to get the abortion with that time, I think it would have meant a lot to me because my daughter wouldn’t have suffered,” Casiano said.

When Casiano was 20 weeks pregnant, a routine scan came back with devastating news: Her baby would be stillborn or die shortly after birth.

The fetus had anencephaly, a rare birth defect that keeps the brain and skull from developing during pregnancy. Babies with this condition are often stillborn, though they sometimes live a few hours or days. Many women around the country who face the prospect choose abortion, two obstetrician-gynecologists told CNN.

But Casiano lived in Texas, where state legislators had recently banned most abortions after six weeks of pregnancy. She couldn’t afford to travel out of the state for the procedure.

“You have no options. You will have to go through with your pregnancy,” Casiano’s doctor told her, she claimed in the lawsuit.

In March, Casiano gave birth to her daughter Halo. After gasping for air for four hours, the baby died, Casiano said during her testimony on Wednesday.

“All she could do was fight to try to get air. I had to watch my daughter go from being pink to red to purple. From being warm to cold,” said Casiano. “I just kept telling myself and my baby that I’m so sorry that this had to happen to you.”

Casiano and 14 others – including two doctors – are plaintiffs in the lawsuit. They allege the abortion ban has denied them or their patients access to necessary obstetrical care. The plaintiffs are asking the courts to clarify when doctors can make medical exceptions to the state’s ban.

Casiano and two other plaintiffs testified Wednesday about hoping to deliver healthy babies but instead learning their lives or pregnancies were in danger.

 Plaintiffs Anna Zargarian, Lauren Miller, Lauren Hall, and Amanda Zurawski at the Texas State Capitol after filing a lawsuit on behalf of Texans harmed by the state's abortion ban on March 7 in Austin, Texas.

“This was just supposed to be a scan day,” Casiano told the court. “It escalated to me finding out my daughter was going to die.”

Lawyers representing the state argued Wednesday that the plaintiffs’ doctors were to blame, saying they misinterpreted the law and failed to provide adequate care for such high-risk pregnancies.

“Plaintiffs will not and cannot provide any evidence of any medical provider in the state of Texas being prosecuted or otherwise penalized for performance of an abortion using the emergency medical exemption,” a lawyer said during the state’s opening statement.

Kylie Beaton, another plaintiff, also had to watch her baby die. Beaton, who didn’t testify this week, learned during a 20-week scan that something was wrong with her baby’s brain, according to the suit.

The doctor diagnosed the fetus with alobar holoprosencephaly, a condition where the two hemispheres of the brain don’t properly divide. Babies with this condition are often stillborn or die soon after birth.

Beaton’s doctor told her he couldn’t provide an abortion unless she was severely ill, or the fetus’s heart stopped. Beaton and her husband sought to obtain an abortion out of state. However, the fetus’s head was enlarged due to its condition, and the only clinic that would perform an abortion charged up to $15,000. Beaton and her husband couldn’t afford it.

Instead, Beaton gave birth to a son she named Grant. The baby cried constantly, wouldn’t eat, and couldn’t be held upright for fear it would put too much pressure on his head, according to the suit. Four days later, Grant died.

Amanda Zurawski of Austin, Texas, center, is the lead plaintiff in the lawsuit.

Experts say that abortion bans in states like Texas lead to increased risk for both babies and mothers.

Maternal mortality has long been a top concern for doctors and health-rights activists. Even before the Supreme Court decision, the United States had the highest maternal mortality rate among wealthy nations, one study found.

Amanda Zurawski, the lawsuit’s lead plaintiff, testified Wednesday that her water broke 18 weeks into her pregnancy, putting her at high risk for a life-threatening infection. Zurawski’s baby likely wouldn’t survive.

But the fetus still had a heartbeat, and so doctors said they were unable to terminate the pregnancy. She received an emergency abortion only after her condition worsened and she went into septic shock.

Zurawski described during Wednesday’s hearing how her family visited the hospital, fearing it would be the last time they would see her. Zurawski has argued that had she been able to obtain an abortion, her life wouldn’t have been in jeopardy in the same way.

“I blame the people who support these bans,” Zurawski said.

Zurawski previously said the language in Texas’ abortion laws is “incredibly vague, and it leaves doctors grappling with what they can and cannot do, what health care they can and cannot provide.”

Pregnancy is dangerous, and forcing a woman to carry a non-viable pregnancy to term is unnecessarily risky when it’s clear the baby will not survive, argued Dr. Mae-Lan Winchester, an Ohio maternal-fetal medicine specialist.

“Pregnancy is one of the most dangerous things a person will ever go through,” Winchester said. “Putting yourself through that risk without any benefit of taking a baby home at the end, it’s … risking maternal morbidity and mortality for nothing.”

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What you should know if there’s no sexual attraction for your partner, according to a therapist | CNN

Editor’s Note: Ian Kerner is a licensed marriage and family therapist, writer and contributor on the topic of relationships for CNN. His most recent book is a guide for couples, “So Tell Me About the Last Time You Had Sex.”



CNN
 — 

A lot of heterosexual male clients are coming into my practice admitting they picked their partner without considering sexual attraction.

During couples therapy sessions with his partner in the room, the man will claim that he doesn’t know why he isn’t experiencing desire. Maybe it’s stress, low testosterone or feeling anxious.

But when I meet with him individually, he often tells a different story. He tells me he picked his partner without prioritizing sexual attraction.

Why would a person pick a potential life partner without feeling the spark of sexual attraction? And can these relationships survive and thrive? Can something like sexual attraction that wasn’t there in the first place be cultivated later?

I’ve talked with many men in their 30s who have told me, “When I found the woman I wanted to marry, she checked all the boxes. Except one.”

Characteristics on that list include “being my best friend,” “will make an amazing mother,” “our friends and families get along so well,” and “she really loves me.” The one box that didn’t get ticked? Sexual attraction — and often the men didn’t even list that quality to start.

I was stunned.

Sexuality is the one thing that really distinguishes a romantic relationship from a platonic one: I find that it’s one kind of “relationship glue” that helps couples stay together through hard times. That’s why I’m puzzled that so many people devalue sex in picking a partner for a long-term relationship.

Research shows that, while physical attractiveness is usually among the most important traits people desire in a romantic partner, it doesn’t actually top the list for men or women,” said Dr. Justin Lehmiller, a research fellow at the Kinsey Institute at Indiana University, a research center dedicated to sexuality. “Traits like intelligence, humor, honesty and kindness are often at least as important, if not more.”

Some men have internalized an “either/or” view of women: those who make great wives and mothers and those who are sexually adventurous, according to Chicago-based sex therapist Dr. Elizabeth Perri.

“I’ve observed this in male patients who are out in the dating world and feel the pressure to pick someone whom they perceive as ‘wife material’ but without sexual attraction, rather than waiting to find a partner who is a better fit both emotionally and sexually,” Perri told me.

This is what you need to fall in love (2014)

Good sex can help protect against psychological distress, including anxiety and depression, helps couples achieve a deeper connection, and improves relationship satisfaction.

“If a relationship is a meal, the sexual portion ought to be considered an integral part of it, such as the protein, instead of a frivolous part like dessert,” says Eva Dillon, a sex therapist based in New York City.

“In my experience, it’s possible for women to cultivate desire for a partner with considerable effort, but if a man does not have desire for his partner at the beginning of a relationship, he will never desire her,” Dillon told me. Why count on sexual attraction coming later when you can prioritize it in a partner and enjoy the benefits from the beginning?”

Still, lower levels of sexual attraction isn’t always a problem for couples, said sexologist Dr. Yvonne Fulbright.

“For some people, a lack of sexual attraction can lead to infidelity or divorce. For others, a lack of sexual attraction only becomes a problem when one tunes into societal expectations around sex and desire,” said Fulbright, who is an adjunct professorial lecturer in the department of sociology at American University in Washington, DC.

“A lot of pressure is being put on couples to maintain active sex lives, and hot ones at that. People have the sense that there’s a type and quality of desire that needs to be achieved, with any disinterest in such considered a problem that needs to be solved.”

Some of my therapist colleagues caution against putting too much emphasis on the importance of immediate sexual attraction.

“We have this misconception that we must be physically attracted to someone when we first meet or there is no relationship potential. That’s just not true,” said sex therapist Dr. Rachel Needle. “Attraction can grow as you get to know someone and experience increased closeness and connection.”

Better way for couples to argue Staying Well _00000411.jpg

The better way for couples to argue (2019)

What should you do if you and your partner are running out of sexual steam? Or if you want to turn up the heat on a relationship that didn’t have any to start with?

Fulbright cautioned against giving any sweeping advice. “Only partners can figure out the best way to manage this challenge in their relationship,” she said.

Non-monogamy may work for some, but not others. Couples need to decide how honest to be with each other, how much this matter is a dealbreaker in staying together versus not, and how much weight should be given to this issue in light of other good things they have going for them,” she added via email.

Don’t feel that all is lost if you’re in a long-term relationship. For some couples, sexual desire can grow over time if they focus on it. “It often isn’t until our 30s that we get comfortable enough to ask for what we want in bed,” Dillon said.

But I refuse to agree with anyone who thinks that married couples will stop having sex anyway so why bother prioritizing sexual attraction.

“Many couples in their 50s can explore and expand their sexuality thanks to maturity and empty nests. For couples in their 60s, 70s and beyond who are able to expand their definition of sex beyond orgasm and co-create intimacy, sex can continue to be vibrant and rich,” Dillon added via email.

And keep in mind, your sexual health is a barometer of your overall health. So if you really are experiencing an inexplicable drop in sexual interest, consider talking to your medical provider. Maybe your testosterone levels really have fallen.

Whatever the source of your lack of sexual interest, just be up front with your partner. Honesty, as it turns out, can be a turn-on (eventually).

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